A-to-I editing of the 5HT2C receptor and behaviour
نویسندگان
چکیده
منابع مشابه
A-to-I editing of the 5HT2C receptor and behaviour.
Site-specific deamination of five adenosine residues in the pre-mRNA of the serotonin 2C receptor, 5HT2CR, alters the amino acid sequence of the encoded protein. Such RNA editing can produce 32 mRNA variants, encoding 24 protein isoforms that vary in biochemical and pharmacological properties. Because serotonin functions in the regulation of mood and behaviour, modulation of serotonin signallin...
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ژورنال
عنوان ژورنال: Briefings in Functional Genomics and Proteomics
سال: 2006
ISSN: 1473-9550,1477-4062
DOI: 10.1093/bfgp/ell006